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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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History Of Taking AKT4, INH, RMP. Have INH Induced Psychosis. Should He Take Medicine Only When Having Fever?

friend was on AKT - 4 for 1st 2 months and than on INH and RMP for next 2 months further diagnosis revealed that he was showing INH induced physcosis, hence both the drugs were closed by the doctor and has taken 4 months treatment is now fine and in very good condition from last 9 months, doctor told he is fine now and just we need to start the akt again only if he is having temperature, but he is perfectly fine now from last almost 1 year now. Please let me know if this is fine, just doctor had told if he continously get temperature again just take and x-ray again and consult him again, but he seems to very perfectly fine. let me know if that is right the tuberculosis drugs are stopped in 4 months, i heard that it should be taken for 6 months that why i am aksing.
Mon, 11 Feb 2013
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General & Family Physician 's  Response
Hello,
Completion of antituberculosis treatment is the foremost priority of tuberculosis (TB) control programs.Interrupted or incomplete treatment increases the risk of treatment failure, relapse of disease, and acquisition of drug-resistant TB.In turn, treatment failure and relapse can increase transmission of TB. 
Although in your friend case,it was essential to stop the treatment because of INH induced psychosis.However,as you rightly pointed out,the treatment has to be completed, since it was incomplete,but it has to be done without the presence of INH in the treatment schedule.
Go by the advise of your doctor or you may even take an alternate opinion,regarding when to start the treatment again.
Thanks
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History Of Taking AKT4, INH, RMP. Have INH Induced Psychosis. Should He Take Medicine Only When Having Fever?

Hello, Completion of antituberculosis treatment is the foremost priority of tuberculosis (TB) control programs.Interrupted or incomplete treatment increases the risk of treatment failure, relapse of disease, and acquisition of drug-resistant TB.In turn, treatment failure and relapse can increase transmission of TB.  Although in your friend case,it was essential to stop the treatment because of INH induced psychosis.However,as you rightly pointed out,the treatment has to be completed, since it was incomplete,but it has to be done without the presence of INH in the treatment schedule. Go by the advise of your doctor or you may even take an alternate opinion,regarding when to start the treatment again. Thanks