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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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History Of D&C Due To Miscarriage. Taken Cytotec Due To Incomplete Procedure. How Long For Tablets To Take Effect?

hi .i had an d and c done because of an early miscarriage (8 weeks)... that proved incomplete by a later ultrasound ...was given 7 cytotec tablets 1 taken vaginally and 3 taken orally and 4 hrs after the remaining 3 tablets taken orally....20 hrs after cramping but no bleeding .....how long does it take for the tablets to go into effect?or do i need to get another dosage or a second d and c?
Thu, 21 Feb 2013
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General & Family Physician 's  Response
Hello, thanks for using HCM.
Cytotec is a prostaglandin which causes ripening of the cervix and induces uterine contractions and or labour if given at the right dosage. However, the duration of onset depends on the method or route of admission and also on the dosage.
One table of cytotec (200mcg) if properly inserted into the posterior fornix (inside the vaginal) is usually enough to induce contractions even in primigravidas (women with first pregnancy) while multigravidae will require as small as one quarter of a cytotec tablet vaginally to have contractions. Three tablets of cytotec taken at once orally has the same effect as a single tablet taken vaginally.
The onset of contractions in the above two methods is usually after 4 hours.
It would have been of great help if the volume of retained product was mentioned after the ultrasound because if small medical treatment with cytotec or ergotamine derivative (not used in some areas) would be okay. However, the next mangement will depend on your clinical presentation,if you are having per vaginal bleedings that are continuing despite the intake of the cytotec then another uterine evacuation will be required. For now, assumming therre is no bleeding or its not worrisome, lets just wait and see how it evolves. You need to be on antibiotics.
Best regard and hope this helps.
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History Of D&C Due To Miscarriage. Taken Cytotec Due To Incomplete Procedure. How Long For Tablets To Take Effect?

Hello, thanks for using HCM. Cytotec is a prostaglandin which causes ripening of the cervix and induces uterine contractions and or labour if given at the right dosage. However, the duration of onset depends on the method or route of admission and also on the dosage. One table of cytotec (200mcg) if properly inserted into the posterior fornix (inside the vaginal) is usually enough to induce contractions even in primigravidas (women with first pregnancy) while multigravidae will require as small as one quarter of a cytotec tablet vaginally to have contractions. Three tablets of cytotec taken at once orally has the same effect as a single tablet taken vaginally. The onset of contractions in the above two methods is usually after 4 hours. It would have been of great help if the volume of retained product was mentioned after the ultrasound because if small medical treatment with cytotec or ergotamine derivative (not used in some areas) would be okay. However, the next mangement will depend on your clinical presentation,if you are having per vaginal bleedings that are continuing despite the intake of the cytotec then another uterine evacuation will be required. For now, assumming therre is no bleeding or its not worrisome, lets just wait and see how it evolves. You need to be on antibiotics. Best regard and hope this helps.