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High postprandial sugar levels, normal fasting sugar. Causes and treatment?

Hi, got my sugar tested 2 weeks back, shockingly it came to 387 mg/dl, am just 32. I stopped eating everything, no sugar, oil nothing and again got my sugar tested last week it came to 410 mg/dl, I was really shocked Then I got m fasting tested it came to 125 mg/dl, am really surprised why there is a deviation.Please guide
Asked On : Sun, 10 Mar 2013
Answers:  2 Views:  91
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General & Family Physician 's  Response
There is nothing unusual in it.
In healthy, nondiabetic subjects, 2-h postprandial blood glucose levels are usually 140 mg/dl. Glucose levels peak at one hour after the start of the meal and then return to preprandial levels within 2–3 hours.
This rise and fall of postprandial glucose levels is due to the first-phase insulin response, in which large amounts of endogenous insulin are released, usually within 10 min, in response to the food intake.. In individuals with type 2 diabetes, the first-phase insulin response is severely diminished or absent, resulting in persistently elevated of postprandial glucose throughout the day.
You must consult a diabetologist and get yourself investigated thoroughly.
Distinction should also be made to see whether it is diabetes type 1 or type 2,by getting C - PEPTIDE estimation done.The treatment is different in both types of diabetes.
Take proper dietary precautions,reduce your weight and regular medicines as advised by your doctor.
Make sure to control your blood sugar levels meticulously to avoid future micro as well as macro vascular complications.
Answered: Tue, 12 Mar 2013
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Internal Medicine Specialist Dr. Akhilesh Dubey's  Response
Welcome to HCM,
It is good that you got screened for blood sugar level,this is most common ways to early detect and start early treatment of diabetes.
In your case even fasting is 125 mg which is also diagnostic of Diabetes and postprandial blood sugar more than 200 mg /dl is diabetic.
In such cases liver produces glucose from protein and fats that is why glucose level is high and passed in urine causes glycosuria.
Please do not do such drastic diet restriction,you must visit Physician or Endocrinologist to properly assess and investigate and treat accordingly do not panic at all.
If there is family history of diabetes,if you are over weight,takes Alcohol,or smoke these all are risk factors.
Once your diagnosis is made and investigated then diet 25 K cal /kg/body weight and regular Physical exercise and oral therapy or insulin will be required as per your need.
Please take care of your health issue to prevent complication acute that is like Keto acidosis and long term complication.
I know your age is just 32 years but diabetes can occur, even if Type I diabetes occurs at younger age and need insulin for control so do not worry .
Take care
Good Luck.
Answered: Tue, 12 Mar 2013
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