Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

162 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

High heart rate from new BP medication

recently been put on amlodipine 10mg daily for my high blood pressure it seems to have work as its now 120 over 78 but my heart rate is now in the 130s sometimes higher sometmes little lower is .this ok ?
Wed, 16 Dec 2009
Report Abuse
Question is related to
Diseases and Conditions ,  
Medical Topics ,  
  User's Response
's  Response
Heart rate in the 130's is too high, and is due to the reflex tachycardia caused by the amlodipine's action of vasodilitation on peripheral arterial smooth muscle. This is a fairly common reaction caused by starting a blood pressure medication that is involved in decreasing systemic resistance. When decreasing systemic resistance in the peripheral vascular system, there is an autonomic response from the CNS to increase blood pressure by 1 of the 3 mechanisms. By decreasing systemic vascular resistance, you're body is compensating this by increasing heart rate or force of contraction, to get itself back to its normal known blood pressure. I would talk to my doctor about reducing the amlodipine dose to 5 mg once daily, and monitoring blood pressure, and pulse to see if the cardiac rate is reduced, and blood pressure is still in goal from the reduced dose, which was the reason for prescribing the medication. If the cardiac rate is still increased above 100 beats per minute, and blood pressure is still at goal, I agree with the other physician about possibly starting a beta-blocker such as atenolol. A specific beta-blocker, such as a beta-1 selective receptor antagonist to control cardiac rate and force of contraction, must be chosen based on any other possible co-morbidities such as renal (kidney) status, or hepatic (liver) function. If you have any kidney concerns (such as decreased renal clearance based on creatinine clearance from labs) then metoprolol is the best choice because it is extensively metabolized by the liver, and won't cause any accumulation of drug due to kidney insufficiency. If you have any liver problems that inhibits metabolism of certain medications, then atenolol should be used because it is primarily excreted through the kidney, and isn't extensively metabolized in the liver as metoprolol is. I hope this helped answer some of your questions, and gave you some insight on what information you and your Dr need to discuss about your blood pressure medications to give you the best benefit, and to best reduce adverse drug reactions. Good luck, and I hope everything gets taken care of very quickly for you.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on

Related questions you may be interested in

doctor1 MD

I have high blood pressure, but most medications I take, will lower my b/P but drops my heart rate too low, around 52. for this reason have difficulty taking any type of medication, beta blockers etc. have high sensitivity to medications. would like to find medication that lowers b/p but not drop heart rate so low. Have gone through a whole list of H.P meds, with my specialists. Have had stress tests and all is O.K.

doctor1 MD

I am on. Blood presure medication, 80 mg of. Valsartin,my blood pressure when I take it is around 110 over 70 when I started on it my bottom number was 90 which I understand is the constant pressure, so I am happy to have that number down . I always take my machine in when I re fill my prescription. It is right on with my doctor. I accidentally filled my medication container with sleeping pills the doctor had given me when my husband passed away 3 years ago that I did not take. It was 5 days before i noticed this , however i did have much better sleeps. I was at the gym and noticed my heart rate was really abnormally high when I was on the tread mill. And decided in would take my blood pressure an it was 130 over 90. So I really don t think that I shoud be reducing my dose ??. Can you advise me???

doctor1 MD

recently my blood pressure has not responded to weight loss and exercise so the doctor placed me on 10mg lisinoprolthat went up to 20mg recently.However the side effects of night coughing, insomnia ,constant urinaton and dizziness meant a return to 10mg and 5mgamopropoline,i think that is the right spelling. Despite this i am still getting chest pain and dizzy spells. I have been told that blood pressure meds can be a hit or a miss until you get the right one. Can any of you relate or give advice.thx

Recent questions on  Amlodipine

doctor1 MD

Hi, I am taking Bystolic and amlodipine for hight blood pressure and synthroid for Hyshimotos Throiditus and my skin has become so thin that my arms are so brused that it looks like someone is mistreating me. (No one is). I bruse at the slightest touch and if just slightly scraped I bleed like a stuck pig. Could some of this be caused by one of my medications?

doctor1 MD

i m on 10mg amlodipine, 5mg bisoprolol and 10mg ramipril. Since last friday (13th) I woke up with a painful right foot. The only thing to change recently was the addition of ramipril, I havent taken it since thursday, should I continue or stop? Any idea what this is and will it pass?

doctor1 MD

I have problem with staying hard while having sex. I take the following meds. Is there any medication that i would be able to take for this problem.

thAMLODIPINE BESYLATE-BENAZEPRIL 10MG-20MG Hypertension (morning 1x)

TEVETEN HCT 600-12.5MG Hypertension (night 1x)

Lexapro Tabs 10MG (morning half)

Lunesta Tabs 3MG Sleep (night 1x)

LANSOPRAZOLE 30 MG Stomach (morning 1x)

ere any medication that i would be able to take for this problem.

doctor1 MD

DEAR :I am a man 39 old - smoking 1 pocket daily - non alkohol -

I have hypertension since 6 year 17/11 . from Two years ago I started using drugs amlodipine 5mg but it side effect gynecomastia so I had to stop it and then used candesartan 16 mg, but in a recent study it is possible to cause cancer so i stoped it.then i take ramipril but it make me very weakness and it does not low my pressure . now i use coreg 6.25 but i have acid uric stones and it arise acid uric and formed new stone . my question is what proper drug can i take for hypertension with this story


doctor1 MD

i have high blood pressure and have been taking Edarbyclor for a number of years. Recently my blood pressure has elevated from 130's over 80 to 175 over 70. I have changed doctors because of moving to a new location and he has changed my...

doctor1 MD

I am taking Amlodipine 5 MG, Clonidine 0.1 MG, Lisinop/HCTZ 20-25 M, and Bystolic 10 MG. I have ran out of my Bystolic and will get them tomorrow. My question is can I take the rest of of high blood pressure meds today with my Bystolic? Thank You!...

doctor1 MD

i feel un easyness and my B P doesn't come in control but when i start walking it start going down .two week before i was using only 2.5 stamilo one time now 5 mg stamilo two times not working. my doctor increase this dose but i am not feeling...