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surface antigen is the earliest indicator of acute infection wihh hepatitis B and is also indicative of chronic infection if its presence persists for more than 6 months. It is useful for the diagnosis of HBV
infection and for screening of blood.
Its specific antibody is anti-HBs.
Hepatitis B e antigen appearing during weeks 3 to 6 indicates an acute active infection at its most infectious period, and means that the patient is infectious.
This is the specific antibody to hepatitis B e antigen. During the acute stage of infection the seroconversion
from e antigen to e antibody is prognostic for resolution of infection.
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