Hello,
There is strong history of
Diabetes in your husband's family.
Hot flashes (
tingling sensation if i'm correct) and associated with pain and that too in left leg only.
If your husband is a smoker or tobacco user advice to quit.
Irritability and
tiredness are signs of
hypoglycemia.
It is advisable for your husband to undergo diabetic screening.
Lifestyle modification, exercise and diet with help.