Hello my constipated friend! Before i say any thing constipation is a symptom not a disease.So you need to rule out the etiology causing it. Let me ask you some questions -Do you have Fewer than 3 bowel movements per week? -Do you Strain? -Do you haveLumpy or hard stools? -D you have Sensation of anorectal obstruction? -Do you have Sensation of incomplete defecation? -Do you have Manual maneuvering required to defecate? -Do you have Abdominal bloating? -Do you have Pain on defecation? -Do you have Rectal bleeding? -Do you have Spurious diarrhea? -Do you have Low back pain? -Do you have Rectal bleeding? -Do you have Abdominal pain (suggestive of possible irritable bowel syndrome [IBS] with constipation [IBS-C]) ? Inability to pass flatus? -Do you have Vomiting? If the answers to these questions is yes the more the severe the constipation. You need Rectal and perineal examination with some Imaging studies to rule out acute processes that may be causing colonic ileus or to evaluate causes of chronic constipation and also sources of sepsis or intra-abdominal problemsif leukocytosis fever or abdominal pains. If the problem still not known then Lower GI endoscopy, colonic transit study, defecography, anorectal manometry, surface anal electromyography (EMG), and balloon expulsion may be used in the evaluation of constipation. Lets talk some cure -You need to focus on dietary change and exercise rather than laxatives, enemas, and suppositories, none of which really address the underlying problem -Also correction of dietary deficiencies, which generally involves increasing intake of fiber and fluid and decreasing the use of constipating agents (eg, milk products, coffee, tea, alcohol) -You can have some of these medications for your onstipation 1)Bulk-forming agents (fibers; eg, psyllium): arguably the best and least expensive medication for long-term treatment 2)Emollient stool softeners (eg, docusate): Best used for short-term prophylaxis (eg, postoperative) 3)Rapidly acting lubricants (eg, mineral oil): Used for acute or subacute management of constipation 4)Prokinetics (eg, tegaserod): Proposed for use with severe constipation-predominant symptoms 5)Stimulant laxatives (eg, senna): Over-the-counter agents commonly but inappropriately used for long-term treatment of constipation There are some newer additions to the treatment management of constipation 1)Prucalopride, a prokinetic selective 5-hydroxytryptamine-4 (5-HT4) receptor antagonist that stimulates colonic motility and decreases transit time 2)The osmotic agents lubiprostone and linaclotide,which are FDA approved for chronic idiopathic constipation, constipation caused by irritable bowel syndrome, and (in the case of lubiprostone) opioid-induced constipation in adults with chronic, noncancer pain Now you said gluten free diet would have helped you only if you have celiac disease. I am sure that has nothing to do with constipation thats more like an autoimune process with diarrhoea and dehydration mostly. Hope i was as clear as humanly possible. I wish you good luck for your Bowel troubles. Regards Dr Khan