I have stage four breast cancer with mets to my bones. I was diagnosed in 2001 with stage 1 and no lymph involvement. I did chemo , two weeks on and one week off from April 4th through July. I had three weeks rest, then did 38 rads every day. The chemo was Adriamiacin, 5Fu, Cytoxin. I went straight into Tamoxafin for almost fiveyears, then was switched to an aromatase inhibitor , (please excuse any misspellings). After approximately 3 - 31/2years I took myself off all of the inhibitors I tried as they gave my such joint pain and my quality of life had deteriorated. I was cancer free for what we think was 5 - 6 years, then the cancer came back in my C7 joint in my neck. I had a fusion there with screws and cages. I started chemo again two weeks on and one week off. I believe the chemo wash called Gamicin? or something like that with taxatere. Added to the mix was Xeloda. After several months, I was taken off because of bad side effects and also after a scan it was determined that the regimen wasn t working. I am now on a new protocol that the FDA is still watching called Affinitor (Eriolimous). I have great hopes for this medicine. It is taken orally at night with Aromasin. Evidently the combination works better together then with just the Affinator alone. Within a short time, I noticed my left leg was swelling quite a bit. One doctor thought it was edema while another thought it was lymphodema. I went to a specialist and he determined I had lymphodema and had a leg wrap made for me. This wrap consists of a plastic covering for the leg which attaches to a machine that blows air into the wrap. There are thre constrictors inside the wrap which push liquids upwards the abdomin, thus getting rid of the fluid. This, however, is temporary. At the end of the day, the swelling is back so the need to do it twice daily is necessary. This, evidently, will last my whole life. Along with the leg swelling, I have noticed that my outside labia majora fills with fluid so that it is uncomfortable to walk, (right side as opposed to the left like the leg).. This starts off fairly normally in the morning but, like the leg, is full by the end of the day causing no pain but an uncomfortable feeling of fullness and is quite hard. I believe that covers everything. If you need more information, please let me know. Thank you, Ellen Schott