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Have addisons disease, seizure disorder. Taking topamax and hydrocortizone. Low platelet count. Frequent blood transfusions needed. Why?

im 33 i have addisons diease and a seizure dysorder i take hydrocortizon 20mg twice a day and topamax 200mg twice a day for the last yr i have had low blood volume and low platelet low enough that i have had to have 12 blood transfusions this yr the sunday after thanksgiving i got a stomach bug that made me end up in the hospital and 2 more units of blood i would like to know why this keeps happening and why now i feel so bad but all my levels are in the low normal range can some one help
Asked On : Sun, 9 Dec 2012
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Internal Medicine Specialist 's  Response

as you have said that you have addison taking hydrocortisone and seizure taking topiramate

When platelets become low with addison then this could means ITP idiopathic thrombocytopenic purpura meaning low platelets as both share same antibodies

Secondily hydrocortisone also causes low platelets

H.Pylori is a famous bug of stomach that cause low platelets and on/off stomach problems with nausea and vomiting

Hope this explains your query , get h.pylori test
Answered: Thu, 29 Aug 2013
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