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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Serotonin Syndrome twice, Major Depressive Disorder, chronic migraines. Taking Celexa. Cure?

I have had Serotonin Syndrome twice as I have Major Depressive Disorder , Recurrent, Severe and Treatment Resistent and also Chronic Migraines, plus many other musco-skeletal issues in my neck and advanced stage TMG. I could keep listing diagnises, but wont. I have had an intractable migraine for 4 weeks, so this week my Neuro has put me on 2 doses of 300mg of Neurontin a day. Currently I am taking 20 mg of Celexa , just went off of 5 mg of Abilify and 60 mg of Straterra as I need a break from the side effects. I couldn t get a definitive answer at the pharmacy.
Mon, 29 Apr 2013
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Psychiatrist 's  Response
Hi there, thanks for asking. Many medications should be used cautiously with Celexa. Combination of many medications with celexa can cause serotonin syndrome. Many medications which abort migrain should not be taken with celexa for avoiding the serotonin syndrome. Serotonin noradrenergic reuptake inhibitors also may do this (one of your medications belongs to this class). You can ask your doctor about this issue more. Best wishes
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Psychiatrist Dr. Jonas Sundarakumar's  Response
Hello and welcome to Healthcare Magic. Thanks for your query.

I understand that you must be going through a difficult time with your multiple problems. You have mentioned that you are on SSRI anti-depressants (Celexa) and that you have been recently prescribed Neuontin by your Neurologist, but you haven't clearly mentioned what your specific question is.

Neurontin is Gabapentin - which is a GABA analog. It has been found useful in the treatment of chronic neuropathic pain. It is also claimed to have a role iin the prevention of migraines, though this hasn't been proven definitively. It is a relatively safe medication and does not have any signioficant interactions with Celexa.

Wish you all the best.

Dr. Jonas Sundarakumar
Consultant Psychiatrist
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Psychiatrist Dr. Nehal Shah's  Response
Thanks for using healthcare magic.

Serotonin syndrome is side effects of selective serotonin inhibitors.

You may get benefited by drugs like serotonin norepinephrine drugs inhibitors like desvenlafaxine or nortryptilline or duloxetine.

Meanwhile you can also do counselling, breathing exercise, yoga or meditation to get rid of Depression,

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Psychologist Dr. K. V. Anand's  Response
Good to have you here in healthcare magic. Your symptoms are notmal.
Please be aware that medications alone cannot cure your problems.
You will be needing psychotherapy sessions
as well as yoga and medication.
There are lot of yoga positions which enhnces body glands and encourages them to perform better.
Please contact a yoga expert
Wish you a good future.
Dr. KV anand
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