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Have Kartagener's syndrome, situs inverses, dextrocardia. Will Kartagener's syndrome be passed to child?

Hello Doctor.. Iam having Kartageners Syndrome , Situs Inverses , and Dextrocardia . iam 28 years old female. I got married 4 years back. from the past 3 years trying to conceive. but not able to conceive. I got some tests recently. Doctor has told My Outer Dynein Arm in abnormal or Stub. In Gynic related Doctor has told one of my Ovary is little small, and egg count also 1.25 like that she told to me. other than that there is no coplications. So iam planning to go for IVF . What are the chances to get Kartageners Syndrome from mother to child? and what kind of precautions can i take while doing IVF for not to get Kartageners syndrome from me to my child. IF we have done any Genetic test while doing IVF, is there any possibility to reduce the Quality of Embriyo? pls let me know ASAP. Iam planning go for IVF in March-2013. ThanQ in Advance.
Asked On : Fri, 1 Feb 2013
Answers:  1 Views:  105
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
Kartagener's syndrome is an autosomal recessive disorder.
Autosomal diseases are ones which are not transmitted by sex chromosomes.
They diseases are transmitted by somatic chromosomes.
Kartagener's syndrome is genetically heterogeneous and it is caused by mutation of a large number of genes.
There is no possibility of transmission of the syndrome as it is an autosomal disease.
IVF involves retrieval of ovum, allowing the ovum and sperms to meet, allowing the zygote to grow in culture plate and final implantation in the uterus.
The entire process is done under the superfivision of an infertility expert.
The choice of embryo is not going to affect the transmission of the syndrome.

Thanks and take care
Dr Shailja P Wahal

Answered: Sun, 8 Sep 2013
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