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Haemoglobin study at 8th month of pregnancy shows no evidence of beta thalassemia or haemoglobinopathy. Meaning?

Hi Am Aishwarya. Am in the 8th month of pregnancy. My haemoglobin level is 9.8 two weeks before. now its 10.4. The report reads as : Abnormal Haemoglobin Study (WB/ HPLC ) Test description Observed value Reference range Haemoglobin F 0.5 0 - 2 % Haemoglobin A 97.2 94.3 - 98.5 % Haemoglobin A2 2.30 1.5 - 3.7 % Haemoglobin D 0 0 % Haemoglobin S 0 0 % Haemoglobin C 0 0 % Haemoglobin E 0 0 % Impression No evidence of . BETA THALASSAEMIA or . HAEMOGLOBINOPATHY . . . . . . . . . . . . Remarks: - 2. Iron deficiency is known to mask HbA2 (False low result) 3. Megaloblastic anaemia is known to elevate Hb-A2 levels (False high result) what does these mean. ? Do i need to take any precaution?
Asked On : Sun, 2 Dec 2012
Answers:  2 Views:  204
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OBGYN 's  Response
Mar 2013

I appreciate your query.

You are suffering from a condition known as anaemia. ( deficiency of haemoglobin )

Also, the most common cause of anaemia in India and other developing countries is iron deficiency anemia ( prevalence is more than 50 % in pregnant women )

Anaemia of pregnancy is generally defined as Hb

At this level of 9.8 / 10.4, you should initiate investigations and treatment because of potentially serious consequences you and the baby.

One reason for this is that in pregnancy, your total body fluid amount increases, so haemoglobin is diluted. But the main reason for iron deficiency anemia is a dietary deficiency of iron, folic acid and protein.

A pregnant woman requires about 2 to 4.8 mg iron every day. To have it from the dietary

sources she must consume 20-48 mg of dietary iron. This is practically impossible because average vegetarian diet does not contain more than 10-15 mg of iron , hence you need to take iron supplements.

Your gynaecologist will prescribe you oral iron tablets, which you must take regularly. There are various brands available in the market, for which you will be guided accordingly. Also include Vitamin C in your diet, as it enhances iron absorption.

You should fortify your diet and include Pulses, cereals, jaggery, Beet root, Green leafy vegetables, meat, liver, egg, fish, legumes, dry beans, and iron enriched cereals and breads.

You should report to your doctor if you have any kind of bleeding disorder, or if your Hemoglobin levels do not improve inspite of therapy.

Hope this helped you.
Answered: Mon, 3 Dec 2012
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OBGYN Dr. Archana Singh's  Response
Thanks for your query,
Haemoglobin is made of globin protein and iron. Haemoglobinopathies are inherited disorder of protein portion. Diagnosis we made on the basis of tests as you stated. Your reports are normal. However, iron deficiency is known to cause false low result of HbA2 and Megaloblastic anaemia is known to elevate Hb-A2 levels . So they may give fast results of HbA2 misleading diagnosis some times.
Probably you are suffering from iron deficiency anaemia or folic acid deficiency , which are common during pregnancy. Apart from supplementary iron and folic acid ,You should take some precautions like-
-healthy diet
-treatment of any infections like worms , urinary tract infection, bleeding piles, dysentry if any.

Hope it helps you..
Answered: Mon, 3 Dec 2012
I find this answer helpful
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