Hello sunil Welcome to Health Care Magic You have negative thinking, tightness of chest, anxiety for about 6 months and you were started on Anti depressants. The medicines you didn t take because of side effects. As when ever any antidepressant is started in a patient slight increase in restlessness, anxiety occurs in first week of therapy along with other side effects (also called as rebound anxiety). These side effects usually go by 1-2 weeks. But as you left medicines and relied on will power, but symptoms reoccured in 6 months. Depression and mixed anxiety is a episodic illness, and it tend to occur again and again. If proper treatment is taken at earlier stage individual becomes well in no time. So medicines are must for most of cases of depression. Medicines like SSRI, SNRI etc are very useful and are devoid of major side effects. Non medical treatment includes a lot of modalities and have effectiveness comparable to medical treatment. Progressive muscle relaxation techniques, meditation, behavioral therapy, deep breathing exercises are main stay of this treatment. For details of these techniques you can take help of Google or you can ask me a question directly. Acupuncture may help to improve symptoms but there are not much studies to support this. Thanks Take Care Dr. Seikhoo Bishnoi