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Got an injection of tpa, bleeding into brain, on life support, fever, high BP. What does this mean?

My friend's father got an injection of tpa and now has bleeding into his brain and is on life support, he also has a fever and high blood pressure. What does this mean? Will he ever recover? Does it take time for the effects to go away? Is it too late for him from having blood in his brain and from maintaining a high temp of 105 which has decreased to 102? Is there anything at all that can counteract tpa or generally be done to help bring him back? He has been on life support for 5 days.
Asked On : Sun, 14 Apr 2013
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Neurologist 's  Response
Nov 2013

Thank you for posting your query.

Tissue plasminogen activator (tpa) is used for treating acute brain stroke (lack of blood flow to brain) and is generally safe and effective. However, in about 5% of cases, bleeding does occur.

If the bleeding in the brain is large, a surgery can be done to remove it.

Fever is most likely due to unrelated causes such as lung infection. This can be treated with antibiotics.

The ultimate receovery depends on the damage caused to brain due to his initial brain stroke as well as bleeding in the brain.

Please get back if you require any additional information.

Best wishes,

Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology)

Senior Consultant Neurologist

Apollo Hospitals, Hyderabad,

My personal URL on this website:

My email:
Answered: Tue, 16 Apr 2013
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