Thanks for query. Glanzmann's thrombasthenia
is due to functional deficiency of GPIIb/IIIa. It may cause mucosal bleedind spontaneously or due to precipitating factors. Local nasal decongestants may increase the chance of nasal bleeding
. Cetrizine may rarely precipitate nasal bleeding in Glanzman's thrombasthenia. I have gone through extensively through the literatures and found that 2nd generation antihistaminics such as desloratidine, loratidine, fexofenadine
may be given safely. Your son may also use fluticasone-azelasine nasal spray
one puff twice daily. But , you should better consult a haematologist before starting these medication.Hope, I satisfied your queries.