Hello Welcome! I would be pleased to answer your question . Accutane increases the chances of Staphylococcal infection of hair Follicles. Your history and clinical picture are suggestive of Recurrent Folliculitis . The first step into figuring out how to prevent this is to get your blood sugar level done (both fasting and after a meal). Diabetes is a common cause of Recurrent Folliculitis. If the sugar level is high then controlling it will prevent new lesions. Besides this here is what I recommend: 1. Mupirocin ointment twice a day for 5-7 days whenever the bumps come. If there is no improvement within 3 days of this then you will require a 5 days course of an oral antibiotic like Dicloxacillin 500 mg three times a day. 2. Dial Antibacterial liquid soap for bathing. Continue this even when asymptomatic. 3. Mupirocin cream twice a day in the inside skin of the nose for 14 days. This may seem strange since you have no symptoms there but this is the commonest site of carriage of the bacteria that causes this condition (staph). Infection keeps recurring from here through carriage by the fingers to other parts of the body. NOTE: Dicloxacilllin and mupirocin will require a prescription so I would recommend discussing my recommendations with your GP/family physician. Bacitracin is an OTC alternative to Mupirocin cream. Please feel free to ask if you have any queries.