Hi and thank you so much for this query. Sitz baths are very important when managing infections around the anal area. This is because they help to kills germs and keep the area bacteria free.. This prevents infections and accelerate healing. It also provides pain relief from the fissures. Betadine cannot be the cause o blood before stools. May be for some other reasons, you had blood before stools but then it should not be directly related to betadine. My advice is that you should continue using it for your sitz baths. Please, most anal fissures are as a result of constipation. You may want to incorporate fibers, fruits, much fluids intake and regular visits to the toilet to prevent this in future. Hope you find this information useful. I wish you a speedy recovery and good health. Dr. Ditah, MD!