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Experiencing fatigue, nausea, high protein levels and ag ratio, not pregnant. Cause of worry?

My daughter in law has been experiencing fatigue and nausea (she is not pregnant) Her protein level is 8.2 , her globulin , calculated is 3.8 and her ag ratio is1.2. She has been feeling Like this for about a month. I am worried about her, what type of dr should she see? What could this be? My e-mail address is YYYY@YYYY . Any info would be greatly appreciated.
Asked On : Tue, 26 Mar 2013
Answers:  2 Views:  409
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General & Family Physician 's  Response

thanks for your query.

Normal ranges for Protein levels are:

Total protein = 6-8.3 mg/dl

Albumin = 3.5-5 gm/dL

Globulin = 2.3-3.5 gm/dL

A/G Ratio = 0.8 - 2.0

So all readings are normal except globulin that is slightly higher.Some globulins are made by the liver, while others are made by the immune system.Many disease can cause high globulin levels.Most common of them are chronic granulomatous diseases like TB and Syphilis. Other causes may be leukemia or other bone marrow disorders,autoimmunity diseases such as lupus or collagen diseases.

As you mentioned she is fatigued and nauseated, it is quite possible she is having any autoimmune disease related to Gestrointestinal tract like ulcerative colitis or carcinoid syndrome and some times kidney diseases.You need other specialized tests to know the exact underlying cause.

Please consult gastroentrologist to exclude GERD and dyspepsia and You may consult immunologist for further assessment.

Hope it helps.

Take care!

Answered: Tue, 26 Mar 2013
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Naturopathy & Yoga Specialist Dr. Ambika Murali Krishnan's  Response
your daughter in law having slight increase in protein, globulin and ag ratio and this increase in value seen in cases like chronic inflammation, liver diseases, multiple myeloma and in rheumatoid arthritis so consult hematologist to rule out the exact cause and for the treatments.
hope this answers your query .
take care.
Answered: Tue, 26 Mar 2013
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