Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
158 Doctors are Online

Elevated liver enzymes. No fatty liver disease. Should I check for other types of hemochromatosis?

I had elevated liver enzymes ( AST 39, ALT 98) so my doctor ordered a number of blood exams ( acute hep, iron TIBC and ferritin, hepatic function, GGt, ANA IFA screen, HIV AB, HIV 1/2). Everything came back normal ( AST down to 20, ALT down to 26) except for total iron- 179 and % saturation at 53%. Iron binding capacity was 338 and Ferritin was 128. Also had an ultrasound of my liver to rule our fatty liver disease , which we did. My doctor thought I could have hemochromatosis , so we checked the HFE gene and it came back that I do not have type and I am not a carrier. My doctor said sometimes fluctuations occur and that I have nothing to worry about since Iron and % saturation are near normal. We will check blood ( hepatic, iron, Ferritin, and TIBC) in a few months. I m a 26 year old male and don t take vitamin supplements or medicines that affect liver function. Do you think I should check for other types of hemochromatosis? Should I see a specialist ( my doctor was not familiar with other types of hemochromatosis)? Thanks
Asked On : Mon, 25 Mar 2013
Answers:  2 Views:  87
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Lab Tests
Medical Topics
General & Family Physician 's  Response
Sep 2013
Thanks for the query to H.C.M. Forum.
A S T & A L T , the normal values of both enzymes are 5-50 IU.
As if value elevated more then 300 then it is specific , otherwise non-specific.
Mere mild to moderate degree elevated level of AST .
However A L T only found in liver but this reading ( 98) is non-specific.
If you haven't any disease or disorder, in my opinion there is no need of any examination.
Good luck.
Answered: Mon, 22 Jul 2013
I find this answer helpful
Cardiologist Dr. Anantharamakrishnan's  Response
Hi friend,
Welcome to Health Care Magic

Elevation 3 or more times the upper limit of normal is called significant and needs extensive investigations.
Now that they have returned to normal, it is reassuring.
There is a battery of advanced investigations (including liver biopsy!) – one may not need...
You just need follow up – a hepatologist (Gastro-enterologist) is the one for liver / a Haematologist is the one for Haemochromotosis – either could guide...
Discuss with your doctor...

Take care
Wishing speedy recovery
God bless
Good luck
Answered: Mon, 22 Jul 2013
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor