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Done blood work. Low vitamin B12 level. Always tired. Negative intrinsic factor. Reason?

I just got complete blood work back and the only thing that came back is a 36.4 mchc level. I seem not to be able to maintain b12 and get once a month b12 shots and then when I stop them my level goes down. It currently around 300. I am always tired. Intrinsic factor came back negative. The doctor didn t seem concerned with the 36.4 level but no answers as to why my b12 level always drops any thoughts
Asked On : Sun, 11 Nov 2012
Answers:  1 Views:  86
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Neurologist 's  Response
Nov 2013

Thank you for posting your query.

There are three common causes of low vitamin b12:

1. Vegetarian diet- as most of the good sources of vitamin B12 are non-vegetarian, so people taking pure vegetarian food may have low levels of vitamin B12.

2. Poor absorption of vitamin B12- due to antibodies against parietal cells or intrinsic fator (which is negative in your case).

3. Malabsoption syndromes- where there is poor absorption of all nutrients including protein, carbohydrate and fats.

Please consult a gastroenterologist for opinion.

Wishing you good health,
Dr Sudhir Kumar MD DM
Answered: Mon, 12 Nov 2012
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