if you are taking too much of a certain medication over an extended period of time it can, if you take a little too much just once it wont but that can cause other problems.... i think a large overdose could probably do it too.
(acetominophen) is a good example and probably one of the more common, a lot of drugs are comboed with acetaminophen
, so people on several medications (especially pain meds and old people who forget what they have and havent taken) take too much and it damages the liver
. the liver regenerates but if the damage is severe enough steatosis
or "fatty liver" sets in