My mother is 88 years old, has been taking synthroid for 30 years. (Her thyroid was removed) Recently, her bloodwork showed her numbers were off so the doctor lowered her dose from .75 to .625. In the meantime, she has been complaining about feeling shaky, listless, low appetite, constitpated, and has a funny taste in her mouth. I notice a decline in cognitive ability; her short memory confuses some details and she does not make logical decisions. Could any of this been related to thyroid condition? The other area of decking health has been her kidneys but the doctor said her numbers were still okay for her age. Also, she tested negative for UTI. Any thoughts?