I am taking Pramipexole 0.125mg.. 2 tabs every night. I was also taking Apple Cider Vinegar in distilled H2O 3 times a day to help with my weight problem. I ve had some very strong cramping in my calves of my legs and my hands. I do have Dupuytrens. (sp). Is it possible that the Pramipexole conflicts with the ACV? I stopped taking the ACV and the cramps stopped. ???