Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. yes,hepatitis b can re ocurr. Reactivation of hepatitis B refers to the abrupt increase in hepatitis B virus replication in a patient with inactive or resolved hepatitis B. Reactivation can occur spontaneously, but more typically is triggered by immunosuppressive therapy . Hope I have answered your query. Let me know if I can assist you further.