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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does antibiotics work well for arthritis knee pain?

I was diagnosed by my orthopedic surgeon with arthritis of both knees ( at the same time).

I accidently cut my thumb with a pocket knife and went to ER where it was sewed up and put on the antibiotic cephalexin (500 mg 4 times a day). On the 6 th day "my knees felt great" (no pain, no crabbing down the stairs holding on to the handrail). The prescription was for 7 days and after that the knee pain returned.

Not convinced there was cause and effect neither I nor my physician knew exactly what to to. After about a month I took the antibiotic for 10 days, and again after 6 or 7 days my knees felt fine and after I stopped the antibiotic returned to my previous state of health.

Any thoughts on why an antibiotic might help my knee pain. (I was tested for Lyme (blood test) and found not to have it. Thanks YYYY@YYYY
Mon, 7 Jul 2014
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Orthopaedic Surgeon, Joint Replacement 's  Response
Hello
Thanks for posting
It is highly unlikely,there msy be s different reason for the knee pain to go.As antibiotics are the one to kill bacteria and have no role in cartilage regeneration.
Hope this helps
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Does antibiotics work well for arthritis knee pain?

Hello Thanks for posting It is highly unlikely,there msy be s different reason for the knee pain to go.As antibiotics are the one to kill bacteria and have no role in cartilage regeneration. Hope this helps