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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Coreg Tablet Cause High Blood Glucose Levels?

I m currently taking Lisiniprol 40 mg once a day in the morning and just switched from Labetalol 100 mg twice a day (morning and before bed) to Coreg 6.25 mg twice a day (morning and before bed). I m a Type I diabetic taking Apidra 5-8 units before meals (3 times a day), and Lantus 18-20 units once a day (evening). I just finished taking my A1C, CBC w diff and platelet count, Comprehensive Metabolic and Urine Microlabumin. Results were fine and my A1C was 6.4. My problem. Since switching to coreg, my fasting glucose reading and readings two after meals have been considerably higher. My readings used to be less than 130 fasting and 130-160 two hours after meals. Now my reading are 220+ fasting and 210+ after meals. I m not sick and there hasn t been any changes to my diet or anything else. Just the switch from labetalol to coreg. My blood pressure readings haven t changed with switch. My morning reading is about 122/80 to 118/76. One drug doesn t seem to be better than the other with regard to my BP readings. Question: I switched from labetalol to coreg without any issues other than the elevated blood sugar. Can I switch back to labetalol hoping my blood sugar returns to where it was? I know both drugs are similar, but would this be safe? Thank you!
Mon, 14 Dec 2020
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Diabetologist 's  Response
Hello,

The tablet mentioned Coreg has no direct effect on blood glucose at all. Because Labetalol and Coreg are both beta blockers only. Both have a similar kind of effect. But Labetalol has both alpha and beta blocking effects.

However, the changes that you have noticed in the glucose levels are unlikely to either of these drugs. You may have to look at Insulin dosage, dietary intake and extent of daily exercise. If need be you can increase either Glargine or the fast acting insulin by 2 to 4 units and monitor the glucose levels till those are brought back to where you need those. Changing to Labetalol is unlikely to help.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Prabhakar Laxman Jathar, Diabetologist
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Does Coreg Tablet Cause High Blood Glucose Levels?

Hello, The tablet mentioned Coreg has no direct effect on blood glucose at all. Because Labetalol and Coreg are both beta blockers only. Both have a similar kind of effect. But Labetalol has both alpha and beta blocking effects. However, the changes that you have noticed in the glucose levels are unlikely to either of these drugs. You may have to look at Insulin dosage, dietary intake and extent of daily exercise. If need be you can increase either Glargine or the fast acting insulin by 2 to 4 units and monitor the glucose levels till those are brought back to where you need those. Changing to Labetalol is unlikely to help. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Prabhakar Laxman Jathar, Diabetologist