Hello Dr. Rynne. Does Atorvastatin cause anxiety or depression? Also, my husband takes that (Atorvastatin 10 mg 1x daily) along with Metformin 1,000MG in AM, 500 during the day and 1,000MG in the evening (so a total of 2,500MG daily) and Invokana 150MG (he breaks up the 300MG tablet) 1x daily. He is experiencing anxiety and depression. He is very nervous. I saw on Mayoclinic and WebMD that the 2 diabetes meds have a lesser side effect of anxiety. I am thinking that maybe the combined drugs are? Or maybe I am looking at older information and they have more incidents? What may I read to learn more?