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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Elevated Live Enzyme Levels Indicate Liver Disease?

Hi doc, i just got my blood test results for AST,at that time I was none fasting, the reading was 66. And my Gamma-GT was 97. I am a 52 year old female. Is my reading very high and does this indicate i have serious liver problem? I dont consume alcohol. I only take supplements such as ginger,garlic,apple cider vinegar,lemon enzyme, vitamin c,vitamin D,curcumin. Please need your advice,thank you
Tue, 19 Jul 2016
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Internal Medicine Specialist 's  Response
Brief Answer:
You need to do further examinations.
You should see a gastroenterologist.

Detailed Answer:
Hello,
Thank you for using HCM.
You have a slight to moderate elevation of the AST and GGT levels. An elevated AST and GGT level suggests that something is damaging the liver but does not indicate specifically what. In general, the higher the level, the greater the damage – to the liver.
The levels of the AST and GGT are not affected by food, but even small amounts of alcohol within 24 hours of a GGT test may cause a temporary increase in the GGT, as well as smoking.
There are different causes of high level of AST and GGT, such liver diseases (hepatitis or cirrhosis), bile duct obstructions, but they may also be due to other conditions, such as congestive heart failure, diabetes, or pancreatitis. They may also be caused by alcohol abuse or use of drugs that are toxic to the liver.
Usually added to AST and GGT, should be evaluated the ALP and bilirubin levels too, in way to make an appropriate differential diagnosis. Except, the results of the above mentioned exams, it would be helpful to take a better medical history of yours, and to understand if you have any signs and symptoms of liver damage such as: weakness, fatigue, loss of appetite, nausea and vomiting, abdominal swelling and/or pain, jaundice, dark urine, light-colored stool, itching (pruritus), etc.
That's why is indispensable to be visited by a gastroenterologist.
He will guide you into further laboratory and imaging exams to detect the cause of the elevated enzymes levels.
Meanwhile do not consume alcohol and don't use medications that may harm liver such as paracetamol, nitrofurantoine (antibiotic) , augmentin (antibiotic). Try to reduce your weight (if obese or overweight), follow a balanced and healthy diet, increase physical activity into at least three days a week, for at least 40 minutes.


Hope this is helpful.
Let me know if you need more clarifications. Otherwise please close and rate the answer.
Kind Regards,
Dr. Juarda
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Do Elevated Live Enzyme Levels Indicate Liver Disease?

Brief Answer: You need to do further examinations. You should see a gastroenterologist. Detailed Answer: Hello, Thank you for using HCM. You have a slight to moderate elevation of the AST and GGT levels. An elevated AST and GGT level suggests that something is damaging the liver but does not indicate specifically what. In general, the higher the level, the greater the damage – to the liver. The levels of the AST and GGT are not affected by food, but even small amounts of alcohol within 24 hours of a GGT test may cause a temporary increase in the GGT, as well as smoking. There are different causes of high level of AST and GGT, such liver diseases (hepatitis or cirrhosis), bile duct obstructions, but they may also be due to other conditions, such as congestive heart failure, diabetes, or pancreatitis. They may also be caused by alcohol abuse or use of drugs that are toxic to the liver. Usually added to AST and GGT, should be evaluated the ALP and bilirubin levels too, in way to make an appropriate differential diagnosis. Except, the results of the above mentioned exams, it would be helpful to take a better medical history of yours, and to understand if you have any signs and symptoms of liver damage such as: weakness, fatigue, loss of appetite, nausea and vomiting, abdominal swelling and/or pain, jaundice, dark urine, light-colored stool, itching (pruritus), etc. That s why is indispensable to be visited by a gastroenterologist. He will guide you into further laboratory and imaging exams to detect the cause of the elevated enzymes levels. Meanwhile do not consume alcohol and don t use medications that may harm liver such as paracetamol, nitrofurantoine (antibiotic) , augmentin (antibiotic). Try to reduce your weight (if obese or overweight), follow a balanced and healthy diet, increase physical activity into at least three days a week, for at least 40 minutes. Hope this is helpful. Let me know if you need more clarifications. Otherwise please close and rate the answer. Kind Regards, Dr. Juarda