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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Cortisone Cream Have A Depressive Effect On Adrenal Glands, Joint Deterioration And Skin Thinning?

Do cortizone creams, when used for a chronic condition like ezcema, have a depressive effect on the adrenal glands , deteriorate the joints and thin the skin? I have used cortizone cream for over 30 years and I have lots of joint pain and damaged skin... I m worried about the effect it has on my ability to produce cortisol on my own. Heather Harrison
Mon, 15 Oct 2012
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Internal Medicine Specialist,  's  Response
Hi Heather,
Thanks for writing in to Healthcare Magic!
Cortisones are hardly absorbale when applied on normal skin. But in your case when applying on highly vascular eczema skin in presence of thinning there are fair chances that you will get systemic effects due to increases absorption and it may lead to pituitary adrenal suppression.
Skin thinning is a well known complication of the topical steroids.
You should get an early morning fasting state serum sample of Corticosteroid levels to define the condition.
If you have any further query please let me know I would try to answer it for you.
Wish you a great health!
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Do Cortisone Cream Have A Depressive Effect On Adrenal Glands, Joint Deterioration And Skin Thinning?

Hi Heather, Thanks for writing in to Healthcare Magic! Cortisones are hardly absorbale when applied on normal skin. But in your case when applying on highly vascular eczema skin in presence of thinning there are fair chances that you will get systemic effects due to increases absorption and it may lead to pituitary adrenal suppression. Skin thinning is a well known complication of the topical steroids. You should get an early morning fasting state serum sample of Corticosteroid levels to define the condition. If you have any further query please let me know I would try to answer it for you. Wish you a great health!