Hello, Thanks for choosing health care magic for posting your query. I have gone through your question in detail and I can understand what you are going through. You have not mentioned which medicines he is on. There are many good antipsychotics available and he should improve with good medicines such as olanzapine or risperidone or aripiprazole etc. If he is a resistant schizophrenia then clozapine can benefit him a lot. Further his appetite can be improved with cyproheptadine. Do discuss these issues with his psychiatrist. Also if he is so emaciated then consider get him admitted in a psychiatry unit until his physical status improves. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. In future if you wish to contact me directly, you can use the below mentioned link: bit.ly/dr-srikanth-reddy Wish you good health, Kind regards Dr. Srikanth Reddy M.D.