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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Diagnosed With Autoimmune Liver Failure, On Steroids. Took Piriteze Tablets, Liver Function Tests High. Relapse ?

Hello there, Back in 2006 i was diagnosed with Autoimmune Liver Failure and spent six weeks in Hospital. They then started me on a cause of Steroids Prednisalone then changed me over to Azzaziaprin. I responded really well to these treatments and then was told that all of my tests were back down to normal so they stopped treatment and i have been fine for three years, just before i went to spain back in July i took some Piriteze tablets which i have read can cause problems with the liver and abnormal liver function tests and that is when i had a blood test a few months ago and was told that the Liver function tests were high (262) is this down to the tablets or is it a relapse? Many thanks, AAA
Thu, 4 Oct 2012
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Internal Medicine Specialist 's  Response
Hi Tom,
usually autoimmune liver disease comes and goes. You can check your liver enzymes one time and they may be normal, and then one month later they may be up and so forth.
Usually a low dose of azathioprine (generic) is enough to keep the disease under control. Keep in mind that if you don't keep it under control (with normal liver enzymes), then the inflammation can progress to "cirrhosis" which when the liver is almost non-functioning and requires a liver transplantation.
Make sure you go to a liver specialist for treatment recommendations. You may even need a liver biopsy.
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Diagnosed With Autoimmune Liver Failure, On Steroids. Took Piriteze Tablets, Liver Function Tests High. Relapse ?

Hi Tom, usually autoimmune liver disease comes and goes. You can check your liver enzymes one time and they may be normal, and then one month later they may be up and so forth. Usually a low dose of azathioprine (generic) is enough to keep the disease under control. Keep in mind that if you don t keep it under control (with normal liver enzymes), then the inflammation can progress to cirrhosis which when the liver is almost non-functioning and requires a liver transplantation. Make sure you go to a liver specialist for treatment recommendations. You may even need a liver biopsy.