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Delayed periods, negative blood and urine pregnancy test, pregnancy ruled out after complete work up. What could be going on?

I am 34yrs old healthy female. I had one pregnancy which resulted in a miscarriage 6yrs ago. Menstrual cycle 26 days never late! My last period was Oct 31 it it is now Dec 26..I have taken one urine and two blood tests about 3 weeks ago all negative. Seen my obgyn and had a COMPLETE work up...all negative. She stated I don t feel pregnant snd she is at a loss. Not stressed out and not on any medications . What is going on???
Asked On : Sun, 30 Dec 2012
Answers:  2 Views:  23
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General & Family Physician 's  Response
If period is delayed by nearly 2mths with blood & urine pregnancy tests -ve,a full check up by obgyn is non suggestive,sonography is done to exclude missed abortion,PCOS,Fibroid uterus.
*After excluding these,Usually , a short course of hormones is given,which is usually followed by withdrawal bleeding.
Many a times menses resume to normal after this. If the following periods are delayed/irregular,it has to be further investigated -
* With consultation of endocrinologist a complete hormonal assesment & management accordingly should be taken over..
* some times diagnostic D&C operation is needed.
I hope I have answered your quiery to satisfy you.
Thank you.
Answered: Tue, 6 Aug 2013
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General & Family Physician Dr. Naresh Jain's  Response
Hello Good Evening,

You have missed period, which is due to some common reason like:

-Stress and anxiety
-Excessive weight loss, or weight gain
-Hormonal imbalance

Any of them can be a cause for your missing period, so please go through proper evaluation to get other causes like hypothyroidism or PCOS.

PCOS (Polycystic ovary syndrome) produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). It is thought to be one of the leading causes of female sub-fertility and the most frequent endocrine problem in women of reproductive age.

The principal features are anovulation, resulting in irregular menstruation, amenorrhoea, ovulation-related infertility, and polycystic ovaries; excessive amounts or effects of androgenic (masculinizing) hormones, resulting in acne and hirsutism; and insulin resistance, often associated with obesity, Type 2 diabetes, and high cholesterol levels.

The symptoms and severity of the syndrome vary greatly among affected women.

Another rare possibility is premature menopause:
In rare cases, a woman's ovaries stop working at a very early age, ranging anywhere from the age of puberty to age 40, and this is known as premature ovarian failure (POF). Spontaneous premature ovarian failure affects 1% of women by age 40, and 0.1% of women by age 30.

So go for a USG, TSH and other investigation to find out the cause of amenorrhoea.


Dr. Naresh Jain.
Answered: Tue, 6 Aug 2013
I find this answer helpful
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