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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Dark Spots On Ankles Of Both Legs. On Dialysis, Antibiotics For Chronic Kidney Disease. Suggestions?

Hi I am suffering from Chronic Kidney disease since Feb2008 , I was on dialysis for 3 days in march 2008 , after that I am taking medicine regularly till date , My problem is I have some dark (black) spots on my both legs ankle, however its not paining but I am not able to use chappals as it looks bad (embarrassing) . can you please advice as it will be permanent or due to drugs that I am taking ? please advice. Thanks and Regards
Mon, 17 Dec 2012
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General & Family Physician,  's  Response
Hello,
Pigmentary alteration occurs in 25-70% of the dialysis population and increases over time. A multitude of uremia-related changes are responsible for the pigmentary alterations. 
 Your hyperpigmentation is due to an increase in melanin production because of an increase in poorly dialyzable beta-melanocyte stimulating hormone.
Frankly speaking there is no proper treatment for this hyper pigmentation and it has been observed that these dark pigmented patches get improved in those patients who receive kidney transplant.
The best would be to discuss this with your treating nephrologist.
Thanks
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Dark Spots On Ankles Of Both Legs. On Dialysis, Antibiotics For Chronic Kidney Disease. Suggestions?

Hello, Pigmentary alteration occurs in 25-70% of the dialysis population and increases over time. A multitude of uremia-related changes are responsible for the pigmentary alterations.   Your hyperpigmentation is due to an increase in melanin production because of an increase in poorly dialyzable beta-melanocyte stimulating hormone. Frankly speaking there is no proper treatment for this hyper pigmentation and it has been observed that these dark pigmented patches get improved in those patients who receive kidney transplant. The best would be to discuss this with your treating nephrologist. Thanks