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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Could Nightmares Be Due To Levopoda Intake?

Hello Have just had thyroxine increased from 175 to 200mcg in last 6 weeks and have started to have a big increase in nightmares. I have always had them but not 3 a night like last night and not so often. Could it be connected to levadopa? Thanks Lou
Thu, 25 Jun 2020
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General & Family Physician 's  Response
Hi.
I've gone through your query and I can understand your anxiety.

Parkinson's disease is treated with medications like dopaminergic agents - levodopa/carbidopa, amantadine,Permax etc. This could disrupt night sleep by 2 ways.
1. By direct effect on the sleep/wake regulation cycle.
2. Because of end of dose symptoms.

By these 2 mechanisms they can cause intense nightmares that disrupt sleep.

Hope I have answered your query. Let me know if I can assist you further. Take care.

Regards,
Dr. Yogapriya V, General and family physician.
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Could Nightmares Be Due To Levopoda Intake?

Hi. I ve gone through your query and I can understand your anxiety. Parkinson s disease is treated with medications like dopaminergic agents - levodopa/carbidopa, amantadine,Permax etc. This could disrupt night sleep by 2 ways. 1. By direct effect on the sleep/wake regulation cycle. 2. Because of end of dose symptoms. By these 2 mechanisms they can cause intense nightmares that disrupt sleep. Hope I have answered your query. Let me know if I can assist you further. Take care. Regards, Dr. Yogapriya V, General and family physician.