Hi, Thanks for writing in. Accutane is a vitamin A derivative isotretinoin and is used for treatment of acne nodules on face. Dermovate is a topical corticosteroid which is used in the treatment of skin inflammatory conditions. The dermovate cream is much more milder than a corticosteroid injection. Creams might cause certain exacerbation however it is not seen in every patient. Taking a cream is a safer option over the injection. Injections give a high dose and might cause side effects in other places. Please use dermovate ointment and if there is any adverse event then stop and consult your doctor urgently. Please do not worry.