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Chronic cough due to eosinophilia. No improvement with medicine. Undergoing hemodialysis for renal failure

Good morning doctor,My father was suffering with chronic renal failure ..he was undergoing hemodialysis twice a week.My query is, since one month he is suffering with chronic cough .We Approached pneumologist also.After blood tests it was diagnosed by doctor that the cough was due to eosinophilia .Inspite of using many medicines..he was not yet relieved from cough as well asthma.Doctor please kindly suggest the remedy for this.My mail Id YYYY@YYYY . Thank you.
Asked On : Sun, 18 Nov 2012
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Allergist and Immunologist 's  Response
Cough due to eosinophilia is NOT a diagnosis as given by your physician. Although it is well known that eosinophil counts go up in asthma, allergies, parasitic infections; I am sure these have been checked and are not relevant here.
You have not mentioned the absolute count or percentage but raised levels in patients with renal failure is mainly due to a vascular cause. If there is any skin rash, vasculitis is likely. If there are eosinophils in the urine, then the diagnosis is interstitial nephritis.
Drug induced eosinophilia like interferon use should be considered if this drug was used, or for that matter blood pressure lowering agents such as ACE-I like enalapril, captopril, trandolapril cause chronic dry cough with raised eosinophil counts.
A thorough review of the causes is required that should be addressed by your renal physician (nephrologist).
I hope that was useful.
Answered: Sun, 18 Nov 2012
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