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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Child Born With Cerebral Atrophy. History Of Vomiting, Grand Mal Seizure, Fever. Side Effects Of Lobazam?

Hi, I have a 2.5 year old son. He was born after 35 weeks of gestation, was developmentally delayed. An MRI report at the age of 10 months showed diffuse cerebral atrophy. He was given physiotherapy from 10 to 16 months of age. He seems to have caught up with developmental milestones now, except that he is not friendly/interested in kids of his age. Also, he is somewhat less active - he can't jump, can't pedal a tricycle to list a few tasks.

He had a series of 3 vomitings, followed by an emeset injection, followed by a complex grand mal seizure at 22 months of age. Another seizure occurred at 28 months of age accompanied with a 103 F temperature for more than 12 hours preceding the seizure. We happened to be in outpatient department of a hospital when this seizure occurred, and he was treated immediately with Lorazepam injection.

Now his doctor has advised us to give a 5mg Lobazam tablet in two doses each day whenever there is fever. I would like to know the side effects of this tablet. Also, what is his prognosis? Is he likely to develop into a normal child? What are the chances to develop epilepsy? What can we do to improve his prognosis and also to reduce the chance of another seizure?

Thanks.
Mon, 19 Aug 2013
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General & Family Physician 's  Response
Hi, child birth at 35 weeks of gestation, is not a factor for defects in the brain, it may be congenital, and genetic.
Aged 2.5 years, when ever he get convulsions after a high fever. These are called fibrile convulsions, secondary to the fever, these will go away after the age of 5 years, don't appear even with high fever. Though possible, less chances for generalised seizures.
I advise you to consult a neurologist for diagnosis and treatment. thank you.
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Child Born With Cerebral Atrophy. History Of Vomiting, Grand Mal Seizure, Fever. Side Effects Of Lobazam?

Hi, child birth at 35 weeks of gestation, is not a factor for defects in the brain, it may be congenital, and genetic. Aged 2.5 years, when ever he get convulsions after a high fever. These are called fibrile convulsions, secondary to the fever, these will go away after the age of 5 years, don t appear even with high fever. Though possible, less chances for generalised seizures. I advise you to consult a neurologist for diagnosis and treatment. thank you.