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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can testosterone undecanoate cause decreased sperm count and gynaecomastia?

Hi,im 21 year old and had low free testosterone my endo asked me to take 40mg capsule of testosterone undecanoate(andrex) 2 caps in morning and 2 in evening for a month i ve studied about oral testosterone undecanoate and found that it has many benefits over other testo drugs like less liver toxity but im also concerned to other problems so my question can this drug cause low or decrease sperm count as i ve read this on many sites that trt can lead to sterility also can his cause gynocomestia should i lower the dose and alos inform me about any other health risks so i can discuss this with my endo.thankyou.
Tue, 6 Sep 2016
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General & Family Physician 's  Response
Testosterone undecanoate is a male sex hormone.
It possible side effects include:
a.      fluid and electrolyte retention
b.      impaired glucose tolerance
c.      increased bone growth and skeletal weight
d.      headache
e.     depression
f.     spermatogenesis suppression causing low sperm count
g.     persistent erection of penis
h.     gynaecomastia
i.     prostatic hyperplasia
These side effects are temporary and seen on long term use of testosterone. On stoppage of testosterone undecanoate, these side effects resolve automatically. This does not lead to sterility. As your testosterone level is low so you need supplement of testosterone undecanoate. It works by replacing or supplementing the testosterone that is naturally made in the body.
Advice
1.     Continue testosterone as suggested by your doctor for 1 month
2.     Do not alter dose by yourself unless suggested by your doctor
3.     Consume less salt
4.     After one month, you again check your serum testosterone level and consult your endocrinologist
5.     If you experience any side effect then contact your endocrinologist. You can write here also on Healthcare magic

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Can testosterone undecanoate cause decreased sperm count and gynaecomastia?

Testosterone undecanoate is a male sex hormone. It possible side effects include: a. fluid and electrolyte retention b. impaired glucose tolerance c. increased bone growth and skeletal weight d. headache e. depression f. spermatogenesis suppression causing low sperm count g. persistent erection of penis h. gynaecomastia i. prostatic hyperplasia These side effects are temporary and seen on long term use of testosterone. On stoppage of testosterone undecanoate, these side effects resolve automatically. This does not lead to sterility. As your testosterone level is low so you need supplement of testosterone undecanoate. It works by replacing or supplementing the testosterone that is naturally made in the body. Advice 1. Continue testosterone as suggested by your doctor for 1 month 2. Do not alter dose by yourself unless suggested by your doctor 3. Consume less salt 4. After one month, you again check your serum testosterone level and consult your endocrinologist 5. If you experience any side effect then contact your endocrinologist. You can write here also on Healthcare magic Thanks