Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
151 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

Can levothyroxine cause stiffness and soreness in calf muscles?

Good Morning - On 8/24 my husband (55 yrs old) was tested and diagnosed with hypothyroidism (TSH: 369.10) and immediatly placed on Levothyroxine (100MCG)medication to lower his TSH level. After a follow-up blood test on 9/21, his TSH level came back at 10.70 and his medication was changed to 112MCG (same brand). Shortly after beginning this medication, he began complaining about stiffness, soreness and tender to the touch of both calf muscles and has difficulty walking up/down stairs as well as normal day to day activities. Upon advising his PCP, he was told you re getting older, you need to slow down . My husband is and always has been quite active and did not have such issues prior to starting this medication. Is it possible that this brand of medication is affecting his calf muscles?
Wed, 24 Feb 2021
Report Abuse
General & Family Physician 's  Response
Hi,

Levothyroxine is a medication used to treat an underactive thyroid gland or hypothyroidism. This thyroid gland makes thyroid hormone that helps to control energy levels and growth. Levothyroxine is taken to replace the missing thyroid hormone. Levothyroxine treatment stimulates the breakdown of glycogen and glycogenic amino acids into glucose. Under hypoxic conditions, lactate production can cause pain or soreness and stiffness in muscle.

Levothyroxine may cause leg cramps, muscle aches, stiffness and soreness or tender to touch of both calf muscles and difficulty in walking, slow down in movement etc. Other side effects of Levothyroxine are increased appetite, weight loss, heat sensitivity, excessive sweating, headache, hyperactivity, nervousness, anxiety, allergic reactions etc. Again, hypothyroidism itself also can cause muscle and joint problems like joint pain and stiffness etc. In case of such type of side effects, you can consult your doctor first.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Recent questions on Thyroid disease


Can levothyroxine cause stiffness and soreness in calf muscles?

Hi, Levothyroxine is a medication used to treat an underactive thyroid gland or hypothyroidism. This thyroid gland makes thyroid hormone that helps to control energy levels and growth. Levothyroxine is taken to replace the missing thyroid hormone. Levothyroxine treatment stimulates the breakdown of glycogen and glycogenic amino acids into glucose. Under hypoxic conditions, lactate production can cause pain or soreness and stiffness in muscle. Levothyroxine may cause leg cramps, muscle aches, stiffness and soreness or tender to touch of both calf muscles and difficulty in walking, slow down in movement etc. Other side effects of Levothyroxine are increased appetite, weight loss, heat sensitivity, excessive sweating, headache, hyperactivity, nervousness, anxiety, allergic reactions etc. Again, hypothyroidism itself also can cause muscle and joint problems like joint pain and stiffness etc. In case of such type of side effects, you can consult your doctor first. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician