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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can klebsiella oxytoca be treated with Norfloxacin?

Can Klebsiella oxytoca by treated with Norfloxacine?

My girlfriend age 71 is treated for Klebsiella Oxytoca with Norfloxacine, but after 10 days using it, she has now much pain in here uretra and bladder. Here doctor refuse to give here more Norfloxacine.
Tue, 12 Jan 2016
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General & Family Physician 's  Response
Hi.
After having gone through the history given in your query, I am of the opinion that your beloved girl friend seems to be suffering from Norfloxacin resistant urinary tract infection caused by Klebsiella species.
The urinary tract infection caused by Klebsiella oxytoca can be very serious since the bacteria have a greater possibility for resistance to antibiotics.
The choice of a specific antimicrobial agent depends on the culture and sensitivity of the urine sample. Usually 3rd-generation cephalosporins ( cefotaxime, ceftriaxone), carbapenems (imipenem/cilastatin), aminoglycosides (gentamicin, amikacin), & quinolones are found to be effective in Norfloxacin resistant infections. These agents may be used as monotherapy or combination therapy like a combination of Gentamicin & Ceftriaxone. If she is allergic to Ceftriazone, Aztreonam or Quinolones are the alternative effective antibiotics.

So, she needs an immediate culture and sensitivity test for her urine sample to select the most suitable antibiotics to eradicate the Klebsiella infection.
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Can klebsiella oxytoca be treated with Norfloxacin?

Hi. After having gone through the history given in your query, I am of the opinion that your beloved girl friend seems to be suffering from Norfloxacin resistant urinary tract infection caused by Klebsiella species. The urinary tract infection caused by Klebsiella oxytoca can be very serious since the bacteria have a greater possibility for resistance to antibiotics. The choice of a specific antimicrobial agent depends on the culture and sensitivity of the urine sample. Usually 3rd-generation cephalosporins ( cefotaxime, ceftriaxone), carbapenems (imipenem/cilastatin), aminoglycosides (gentamicin, amikacin), & quinolones are found to be effective in Norfloxacin resistant infections. These agents may be used as monotherapy or combination therapy like a combination of Gentamicin & Ceftriaxone. If she is allergic to Ceftriazone, Aztreonam or Quinolones are the alternative effective antibiotics. So, she needs an immediate culture and sensitivity test for her urine sample to select the most suitable antibiotics to eradicate the Klebsiella infection.