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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Inflammatory Drug Cause 2nd Stage Of Renal Failure?

I was just in the hospital for a surgery and my dr said I need to see some one about kidney failer that the blood work shows 2nd stage of renal failer. could medication be causing this i take an inflamation drug? what are bad levels on blood work, and symptons
Tue, 30 Apr 2019
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General & Family Physician 's  Response
Hi,

Yes, nonsteroidal anti-inflammatory drugs (NSAIDs), such as Ibuprofen (Advil, Motrin) or naproxen causing diminished kidney function.

Chronic kidney disease is divided into five stages of increasing severity:

Stage I: Slight damage to the kidney(s) damage.

Stage II: Mild decrease in kidney function.

Stage III: Moderate decrease in kidney function.

Stage 4: Severe decrease in kidney function.

Stage 5: Kidney failure, Lifestyle changes such as losing weight, exercising, meditating, eating less salt.

Keeping yourself hydrated and drinking less alcohol can help lower your blood pressure and kidney damage.

Smoking is a risk factor for faster progression of kidney disease, so stopping smoking can also help slow progression.

Renal function will recover in most patients after withdrawal of NSAID. Steroids may aid recovery in patients with interstitial nephritis who do not improve after stopping NSAID therapy.

Normal creatinine levels are from 1 to 1.5 mg per deciliter and GFR more than 90 mL/min/1.73 m2 is normal.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr AJEET SINGH, General & Family Physician
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Can Inflammatory Drug Cause 2nd Stage Of Renal Failure?

Hi, Yes, nonsteroidal anti-inflammatory drugs (NSAIDs), such as Ibuprofen (Advil, Motrin) or naproxen causing diminished kidney function. Chronic kidney disease is divided into five stages of increasing severity: Stage I: Slight damage to the kidney(s) damage. Stage II: Mild decrease in kidney function. Stage III: Moderate decrease in kidney function. Stage 4: Severe decrease in kidney function. Stage 5: Kidney failure, Lifestyle changes such as losing weight, exercising, meditating, eating less salt. Keeping yourself hydrated and drinking less alcohol can help lower your blood pressure and kidney damage. Smoking is a risk factor for faster progression of kidney disease, so stopping smoking can also help slow progression. Renal function will recover in most patients after withdrawal of NSAID. Steroids may aid recovery in patients with interstitial nephritis who do not improve after stopping NSAID therapy. Normal creatinine levels are from 1 to 1.5 mg per deciliter and GFR more than 90 mL/min/1.73 m2 is normal. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr AJEET SINGH, General & Family Physician