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You can take the medicines after good meals .
If you have heaviness you can take 1 glass of cold
If you take the medicines say about an hour after food then better take it with 1 glass of milk.
If you don't want or don't like milk then you can take a antacid
like ranitidine-300mg twice a day with medicines.
(cold milk itself is used as antacid)
Hope that answers your question.