Dear Mrs. Sheela I went through your query and appreciate your concern for your daughter. Prodep is Fluoxetine which is an anti-depressant medication. Anti-depressant medications should be continued for few months even after the patient feels alright in order to prevent any relapse or recurrence of symptoms. Her having pain in wrist might be a result of discontinuation effect of fluoxetine. Whenever the anti-depressant medications have to be stopped, they should be tapered and withdrawn rather than stopping suddenly to prevent any discontinuation symptoms. In your daughter s case, I would advise that you discuss with the psychiatrist about continuation of fluoxetine. I do hope that i was able to help with your problem. Best wishes, Dr. Sunil Gupta