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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Body Become Immune To The Clonazepam And Zoloft Medicine After Long Term Use ?

Hi, im taking clonozapam and zoloft for panic disorder and depression and it seems like their starting not to To work anymore. Ive been taking them for a little over a year now, is my body becoming Immune to the pills? What should i do? Please help...
Fri, 6 Jan 2012
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General Surgeon 's  Response
welcome to healthcaremagic
generally theses group of drugs take about 21days to act if it is taken properly..in your case u either need to increase the dose or change your medications..consult a good psychiatrist..
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Psychiatrist Dr. Keerthish Shetty's  Response
Following points that can be considered:
1. Ensuring proper compliance (skipping doses and discontinuing medication once in a while does not help)
2. Second opinion for review of diagnosis (all good doctors welcome second opinion in difficult cases who are not responding to treatment)
3. Addition of non pharmacological methods of treatment (like cognitive behaviour therapy for panic disorder)
4. Addressing on going stressors which may be contributing to the illness
5. Good family support and occupational rehabilitation always helps
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Can Body Become Immune To The Clonazepam And Zoloft Medicine After Long Term Use ?

welcome to healthcaremagic generally theses group of drugs take about 21days to act if it is taken properly..in your case u either need to increase the dose or change your medications..consult a good psychiatrist..