Hello I appreciate your concern Looking at your description you are having multiple problems with anus, vaginal wall and throat with swollen lymph glands I would like further information to help you better Your age and relevant medical history like diabetes or other metabolic disease. are you having problem of chronic constipation? You need a physical check up so I would advise you to consult your doctor for clinical examination and a battery of tests like blood for hemoglobin, CBC, Liver function test and an X ray chest You may require a course of antibiotics under supervision of your doctor Meanwhile please follow these guidelines Avoid constipation by taking liquid paraffin at bed time Have lots of fresh fruits and vegetables You can apply lignocaine ointment for fissure or piles Maintain good hygiene Have multivitamins and food supplements Hope this answers your question Thanks and best wishes