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Can I Use Aspirin As An Anticoagulant Treatment For Protein S Deficiency?
Can I use aspirin as an anticoagulant treatment for Protein S Deficiency? I am a police officer and the city I work for is going to make me retire because I take Warfarin. I had a DVT/PE and have been taking Warfarin ever since. Also, I want to be retested because I think my test was a false positive for the protein s deficiency. When I was released from the hospital I took shots for about 5 days then started taking the Warfarin. About 5 weeks later I had blood work done and was later told I had I the protein S deficiency. I have recently learned that my results could be a false positive because because I was on the Warfarin. I recently saw a hematologist who said he would not take the chance having me retested because I could get another clot in the 4-6 weeks needed to be off the medicine in order to get properly retested. Family History: I am 46 and my mother passed away due to DVT/PE. My sister had DVT. All 3 of my sisters have tested negative for the protein S deficiency. I am really want to be retested and stop taking Warfarin. I was hoping and Aspirin could be an alternative. I am healthy, active, 5 11 205 pounds. Thank you, John
I understand your reasonable concern. Unfortunately warfarin targets a different mechanism than aspirin. Aspirin blocks platelet function. Warfarin acts on the coagulation cascade. Some protection could be achieved with aspirin because it would prevent platelet participation in the thrombosis but the initiating event (the faulty coagulation cascade) cannot be influenced.
There alternatives to warfarin which target the activated factor Xa. Brilique is one of them. It does increase your bleeding tendency though and I suppose you may have similar problems with it too.
I hope I've helped. Contact me again if you'd like more information.
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Can I Use Aspirin As An Anticoagulant Treatment For Protein S Deficiency?
Hello John, I understand your reasonable concern. Unfortunately warfarin targets a different mechanism than aspirin. Aspirin blocks platelet function. Warfarin acts on the coagulation cascade. Some protection could be achieved with aspirin because it would prevent platelet participation in the thrombosis but the initiating event (the faulty coagulation cascade) cannot be influenced. There alternatives to warfarin which target the activated factor Xa. Brilique is one of them. It does increase your bleeding tendency though and I suppose you may have similar problems with it too. I hope I ve helped. Contact me again if you d like more information. Kind regards!