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Can I Have Renal Transplant When I Am On Medication For HCV Infection ?
i am a diabitic type two patient. I am in dyalisys patient from one year and planned to transplant bo the kidneys. at the time of bood testing i found hcv rna positive GNA TYPE 1, even thouhgh i had under gone syngle use dialiazer through the period of dialisys. I had bood trnsfusion once during the month of march 2009. I under took treatment for hcvrna . I took PEgasysy interferon 180mcg treatment . After 8 injections my level of hcv rna become negative. i took further two inejction already. Now gastronics dr. says , i have to take further 12 injections to completely eradicate the hcv rna virus frommy blood . But the nephrologysts is assuring us to go head for kidney transplantation. HOW TO GO HEAD SIR. I AM AGED ABOUR 46 YEARS. kindly suggest the case and oblige thanking you shrinivas
Wed, 25 Jan 2012
Hi Shrenivas
> i am a diabitic type two patient. I am in dyalisys
patient from one year and planned to transplant bo
the kidneys. at the time of bood testing i found hcv
rna positive
-----------------------------------
Dialysis has become a predominant mode of hcv
transmission in world inspite of best dialysis
practices.
--------------------------------------------------
> GNA TYPE 1:
This is difficult to treat genotype and is
associated with poorer outcome.
--------------------------------------------------
>I under took treatment for hcvrna . I took PEgasysy
interferon 180mcg treatment . After 8 injections my
level of hcv rna become negative. i took further two
inejction already. Now gastronics dr. says , i have
to take further 12 injections to completely
eradicate the hcv rna virus frommy blood.
Atleast 48 weeks of treatment is recommended for
genotype 1. Shorter duration is associated with
lower response rate and higher relapse (recurrence).
------------------------------------------
> But the nephrologysts is assuring us to go head
for kidney transplantation.
If you are maintaining a good health on dialysis,
completion of 48 weeks of treatment will be
advisable. But if you are rapidly deteriorating, and
not able to tolerate dialysis, your doctor may
suggest early kidney transplant with following
caveats
1. HCV may recur
2. It is not possible to treat HCV
posttransplant
3. Your liver may suffer rapid damage in
posttransplant period.
4. You may develop HCV related problems like
cryoglobulinemia
Talk to your nephrologist
DR VAIBHAV BANAIT,
MD, DNB, DM
Consultant gastroenterologist
> i am a diabitic type two patient. I am in dyalisys
patient from one year and planned to transplant bo
the kidneys. at the time of bood testing i found hcv
rna positive
-----------------------------------
Dialysis has become a predominant mode of hcv
transmission in world inspite of best dialysis
practices.
--------------------------------------------------
> GNA TYPE 1:
This is difficult to treat genotype and is
associated with poorer outcome.
--------------------------------------------------
>I under took treatment for hcvrna . I took PEgasysy
interferon 180mcg treatment . After 8 injections my
level of hcv rna become negative. i took further two
inejction already. Now gastronics dr. says , i have
to take further 12 injections to completely
eradicate the hcv rna virus frommy blood.
Atleast 48 weeks of treatment is recommended for
genotype 1. Shorter duration is associated with
lower response rate and higher relapse (recurrence).
------------------------------------------
> But the nephrologysts is assuring us to go head
for kidney transplantation.
If you are maintaining a good health on dialysis,
completion of 48 weeks of treatment will be
advisable. But if you are rapidly deteriorating, and
not able to tolerate dialysis, your doctor may
suggest early kidney transplant with following
caveats
1. HCV may recur
2. It is not possible to treat HCV
posttransplant
3. Your liver may suffer rapid damage in
posttransplant period.
4. You may develop HCV related problems like
cryoglobulinemia
Talk to your nephrologist
DR VAIBHAV BANAIT,
MD, DNB, DM
Consultant gastroenterologist
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