Hi, Thanks for choosing HCM All9 contains all the amino acids required to fulfill the need of mother and child during pregnancy these amino acids help in building up of proteins folic acid helps in preventing neural tube defect in the fetus calcium may interfere with absorbtion of iron ,so take them at different times...........one in the morning and one in the night(preferably iron in the night so that you may not feel nausea the whole day) but folic acid has no problem with both as far as i know so you can take folic acid either with calcium or with iron similarly All9 can also be taken in any combination Neogest used to avoid miscarriages, do cause some fetal risk during pregnancy but if your doctor thinks that benifits outweigh the risks you can proceed with it so talk to your doctor and proceed wish you good luck hope i answered your query feel free to contact me for further queries thank you