Welcome to healthcare Magic!
Thee symptoms your wife iis sufferin is indicative of somee serious systemic inflammation.
she can be having a viral or bacterial infection or some times such symptoms mayy bee part of an autoimmune pathology like rheumatoid arthritis
also present like this.
For a fine tuning of diagnosis she needs to be evaluated by a local physician and should get investigated.
delaying may affect the outcome.
I hope the advise would be informative and useful for you.