I can understand your concern with the drug interactions. It is very important to keep tract of the drug interactions if a person is taking multiple drugs. If a patient is under the care of multiple physicians, such interacting drugs can be prescibed by them. the awnser to this problem is to always consult your Primary care physician about htese medications. I will try my best to list all the drug interactions that happen with the medications that you are taking 1) Barbiton (phenobarbitol) can affect the liver enzymes and decreases the amount of ecosprin gold (atorvastatin) and Repace (losartan) in the blood. This decreases the effect of these drugs. 2) Syndopa-110 (Carbidopa and Levodopa) and Barbitone (phenobarbitol) can interact with Repace (Losartan) to increase its effect and lead to greater decrease in blood pressure which can sometimes manifest as weakness. 3) Barbitone (Phenobarbitol) interacts with Dizitac (Cinnarizine) and lead to drowziness and decrease mental function. I would recommend that you should visit your physician and review your drugs. Thank you for giving us the opportunity to help you. I hope this awnsers your question. If you have any further questions please feel free to contact. Have a nice day. Sincerely, Dr. Waqas Hayat